Chemistry Seminar: Cucurbit[n]uril Molecular Containers: From Basic Science to Biomedical Applications

Featuring Dr. Lyle Isaacs, Professor of Chemistry, University of Maryland

Image of our speaker, Dr. Lyle Isaacs, Professor of Chemistry, University of Maryland
Dr. Lyle Isaacs, Professor of Chemistry, University of Maryland

The Department of Chemistry Presents, via In Person and Online Zoom Presentation: Lyle Issacs, PhD, Professor of Chemistry, University of Maryland

In this talk I will present our recent work on the preparation and use of macrocyclic and acyclic CB[n] (1 and 2) in biologically relevant applications.  For example, I will discuss the use of acyclic CB[n] as a solubilizing excipient for insoluble drugs,[1] as a reversal agent for neuromuscular block as well as hyperlocomotion induced by drugs of abuse (e.g. methamphetamine),[2] and our recent discovery of ultrahigh affinity sulfated pillararenes.[3]

Google map embed